ABSTRACT This study evaluated the technical and economic feasibility of long-acting progesterone (P4LA) supplementation in Nellore cows by assessing conception rates, pregnancy loss, cost per pregnancy, and progeny performance. A total of 452 cows (with a body condition score, BCS, ranging from 2.25 to 3.75) underwent a conventional three-handling timed artificial insemination (TAI) protocol. After TAI (D0), cows were allocated to a control group (n = 234; saline solution) or a P4LA group (n = 218; 150 mg, intramuscular, IM, […]