Twelve Nellore cattle fitted with ruminal and duodenal cannulas were used to investigate the effects of increasing dietary crude protein level (7, 10, 13, and 15%) on intake, ruminal and total tract digestibility of nutrients, microbial protein synthesis, degradabilities of corn silage, corn starch, and cottonseed meal, and ruminal metabolism. Animals were blocked by sexual category (heifers, bulls and steers averaging 254.8, 285.1, and 265.6 kg of body weight, respectively) and then assigned to one out of three Latin squares. […]