R. Bras. Zootec.01/Apr/2000;29(2):443-51.
Algorithm to calculate proportion of genes identity by descent, to map QTL in half-sibs families
DOI: 10.1590/S1516-35982000000200018
The development of linkage maps has stimulated the search for methods to map genes involved with quantitative trait loci (QTL). A sib par method based on the relation between individuals identic by descent (IBD) has been used to map QTLs. The objective of this paper was to extend the HASEMAN and ELSTON (1972) method to estimate the proportion (p) of genes IBD in half-sib families. The obtained results suggested that the used procedures were efficient to estimate p even when parents genotypes were partial or totally unknown.
Algorithm to calculate proportion of genes identity by descent, to map QTL in half-sibs families
Keywords: genes identity by descent; half-sibs; epistasis